My lab has been developing computational resources, prediction algorithms, web servers, databases and big data analysis to solve biological problems since 2004 with emphasis on Antivirals (siRNA, miRNA, peptides, compounds), viromics, genome-wide RNAi, vaccine epitopes, Quorum sensing/Bio-film, CRISPR/Cas based genome editing and viral NGS data analysis (http://bioinfo.imtech.res.in/manojk/). We are focusing on the development of antivirals against dengue/flaviviruses and Indian virome exploration using NGS approach. Earlier, I worked at National Centre for Diseases Control, Delhi from 1996 to 2004 in molecular characterization of etiological pathogen involved in major epidemics/outbreaks in INDIA under biosefety requirements (BSL-2/3) especially Dengue, HIV, influenza, Hepatitis, etc.

• Gupta, A.K., Kaur, K., Rajput, A., Dhanda, S.K., Sehgal, M., Khan, M.S., Monga, I., Dar, S.A., Singh, S., Nagpal, G., Usmani, S.S., Thakur, A., Kaur, G., Sharma, S., Bhardwaj, A., Qureshi, A., Raghava, G.P.S., Kumar, M*. (2016) ZikaVR: An Integrated Zika Virus Resource for Genomics, Proteomics, Phylogenetic and Therapeutic Analysis. Sci Rep. Sep 16;6:32713. doi: 10.1038/srep32713
• Rajput, A., Kaur, K., Kumar, M.*. (2016) SigMol: repertoire of quorum sensing signaling molecules in prokaryotes. Nucleic Acids Res. Jan 4;44(D1):D634-9. doi: 10.1093/nar/gkv1076.
• Kaur, K.#, Gupta, A.K.#, Rajput, A.#, Kumar, M.* (2016) ge-CRISPR - An integrated pipeline for the prediction and analysis of sgRNAs genome editing efficiency for CRISPR/Cas system. Sci Rep. Sep 1;6:30870. doi: 10.1038/srep30870.
• Dar, S.A., Gupta, A.K., Thakur, A., Kumar, M.* (2016) SMEpred workbench: a web server for predicting efficacy of chemically modified siRNAs. RNA Biol. 13(11):1144-1151. DOI: 10.1080/15476286.2016.1229733.
• Thakur, N., Qureshi, A., Kumar, M.*(2012) AVPpred: Collection and prediction of highly effective antiviral peptides. Nucleic Acids Res. Jul;40(Web Server issue):W199-204. doi: 10.1093/nar/gks450.